SYFPAC® SECUREJECT®

PREFILLED SYRINGES

SYFPAC® SECUREJECT® is designed for the manufacturing of Prefilled Syringes (PFS) and injection devices using BFS technology. It is the perfect choice for high production of plastic syringes from 0.5ml to 20ml. Starting from the polymer granule, the syringe is formed, filled and sealed inside one machine in only 16 seconds, under aseptic conditions.

Small Volume Parenterals
 
APPLICATIONS


Vaccines, injectables, biologicals

VOLUMES AND MOULDS


From 0.5ml to 20ml

CLEAN ROOM


6.5 x 12 x 3.9 m

PRODUCTION RATE


Up to 5.100 units per hour

HIGH FLEXIBILITY


PE, PP, HDPE

SOLUTION PROPERTIES


From 4°C to 30°C

APPLICATIONS

  • Vaccines
  • Biologicals
  • Subcutaneous
  • Intramuscular
  • Anti-coagulants
  • Anti-thrombotics

THE MACHINE

VOLUMES AND MOULDS

On SYFPAC® SECUREJECT® machine there are several designs available: from squeezable single dose syringe (with or without inserts) to a more standard design including piston and one or two inserts. Volumes can range from 0.5ml up to 20ml and the needle can be inserted or added later to a luer connector

CLEAN ROOM

The compact size of the machine allows for reduced clean room dimensions of only 60 sqm, where only class C is required. Syringes are produced under grade A inside one machine only, with no need of additional steps that involve a larger clean room. 

PRODUCTION RATE

SYFPAC® SECUREJECT® machine can produce up to 5.100 syringes per hour, as the syringes can be made, filled and sealed within 16 seconds per cycle. Suitable for mass production, the machine can work 24/7. Its robust construction, together with its smart preventive maintenance program, prevents failures and unexpected expensive maintenance.  

HIGH FLEXIBILITY

Different types of polymers can be used on the same machine (PP, PE, HDPE), with no need to change the mould nor requiring complicated operations. By reducing the production steps and the cost of secondary packaging, the cost of prefilled syringes is significantly lower than normal syringe manufacturing.

SOLUTION PROPERTIES

SYFPAC® SECUREJECT® can safely fill temperature sensitive formulations like biologicals and vaccines, with some basic modifications to keep temperature solution below the requested rangeApart from solutions with viscosity similar to water, pastes and creams can also be filled.

DETAILS

Brevetti Angela has been producing prefilled syringes on BFS technology for more than 20 years. The innovation in this field is constant and we are currently at the fifth generation of prefilled syringes.

Production cost of a pre-filled syringe on BFS is between 8 and 12 cents per unit, making it the lowest manufacturing cost compared to glass or pre-moulded polymer containers.

Premeasured dosage prevents risk of dosage errors and minimizes drug waste. A prefilled syringe eliminates the possibility of reuse and consequent cross infection or risk of contamination.

pre-filled syringe is ready to use and easy to handle, by healthcare professionals as well as by patients.

The machine HMI is designed to be user friendly and intuitive, while also following the requirements of CFR 21 for data integrity. The machine automatically keeps track of the necessary maintenance based on work hours and cycles. The operator is then notified via the HMI.

Cleaning In Place, Sterilization In Place, drying, and integrity test are performed automatically

SECUREJECT

  • PREFILLED SYRINGES

  • LOWEST PRODUCTION COST

  • NO RISKS

  • READY TO USE

  • USER FRIENDLY HMI

  • CIP & SIP

CONTACT US

We speak English, Italian, Spanish and Hindi

Want to get a quote, discuss your project or just get to know more about BFS technology? Contact us and we will be happy to help you.

+39 0444 474200

sales@brevettiangela.it