Technology
The Blow-Fill-Seal
Technique
The
blow-fill-seal technique can eliminate human dust and also as maintain a
clean environment in the vicinity of the open bottle. The SYFPAC uses
blow-fill-seal technique to automatically carry out following operations:
1) extrusion of plastic
granulate into a parison at 170°-220°C
2)
blow-molding of the
parison into a container with sterile air
3)
aseptic filling of the
sterile filtered pharmaceutical solution
4)
hermetic sealing of the filled container
The process takes place in a single machine under a controlled
environment that enables the packaging of a parenteral solution in an
aseptic manner, with the following advantages:
a)
less overall
floor space requirement
b)
lower personnel
requirements
c)
lower clean
room requirements
d)
lower logistical
problems
storage of the empty container.
Short
description about BLOW FILL SEAL
(in
.pdf format)
Blow-Fill-Seal
Technique
Primary
Packaging
Molds
& Materials
Control
Systems
